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Article

Molecular Evidence for Mitochondrial Dysfunction in Bipolar Disorder

1 Mar 2004

Abstract excerpt

BACKGROUND: The disease mechanism of bipolar disorder remains unknown. Recent studies have provided evidence for abnormal gene expression in bipolar disorder. OBJECTIVE: To determine the expression of 12558 nuclear genes in the human hippocampus in healthy control subjects and those with bipolar disorder or schizophrenia. DESIGN: We used gene arrays to study messenger RNA expression. Data were verified with a...

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PMID: 14993118
DOI: 10.1001/archpsyc.61.3.300

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