Article
Clinical significance of PlA polymorphism of platelet GP IIb/IIIa receptors during long-term VAD support.
The Annals of thoracic surgery - 1 Mar 2004
Potapov Evgenij V, Ignatenko Stanislav, Nasseri Boris A, Loebe Matthias, Harke Cornelia, Bettmann Martin, Doller Anke, Regitz-Zagrosek Vera, Hetzer Roland
Abstract excerpt
BACKGROUND: Although bleeding and thromboembolism remain major complications after implantation of ventricular assist devices (VADs), no standard anticoagulation protocols are available. Genetic polymorphism of platelet glycoprotein IIb/IIIa may contribute to the development of complications. The present study demonstrates a relationship between the PlA genotype and postoperative complications in patients...
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