Article
A novel transcription regulatory complex containing death domain-associated protein and the ATR-X syndrome protein.
The Journal of biological chemistry - 7 May 2004
Tang Jun, Wu Shaobo, Liu Hongtu, Stratt Rachael, Barak Orr G, Shiekhattar Ramin, Picketts David J, Yang Xiaolu
Abstract excerpt
Death domain-associated protein (Daxx) is a multi-functional protein that modulates both apoptosis and transcription. Within the nucleus, Daxx is a component of the promyelocytic leukemia protein (PML) nuclear bodies (NBs) and interacts with a number of transcription factors, yet its precise role in transcription remains elusive. To further define the function of Daxx, we have isolated its interacting proteins in...
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