Article
Inducible nitric oxide synthase gene (NOS2A) haplotypes and the outcome of hepatitis C virus infection.
Genes and immunity - 1 May 2004
Yee L J, Knapp S, Burgner D, Hennig B J W, Frodsham A J, Wright M, Thomas H C, Hill A V S, Thursz M R
Abstract excerpt
Inducible nitric oxide synthase (iNOS) is an important molecule involved in the host defense against infectious agents. iNOS is encoded by the NOS2A gene and well-defined haplotypes exist with respect to this gene. We examined whether these haplotypes were associated with the outcome of hepatitis C virus (HCV) infection in 619 Caucasian patients from seven European liver centres. We observed five major...
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