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Article

Modifying RESA protein peptide 6671 to fit into HLA-DRbeta1* pockets induces protection against malaria.

Biochemical and biophysical research communications - 19 Mar 2004

Alba Martha Patricia, Salazar Luz Mary, Vargas Luis Eduardo, Trujillo Mary, Lopez Yolanda, Patarroyo Manuel Elkin

Abstract excerpt

6671 is a non-immunogenic, conserved high activity red blood cell binding peptide located between residues 141 and 160 of the Plasmodium falciparum RESA protein. This peptide's critical red blood cell (RBC) binding residues have been replaced by amino acids having similar mass but different charge to change their immunologic properties. Three analogues (two of them immunogenic and protective and one immunogenic)...

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Source

Identifiers

PMID: 14985134
DOI: 10.1016/j.bbrc.2004.02.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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