Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Development of a highly sensitive RT-PCR luminometric hybridization assay for human telomerase reverse-transcriptase beta-plus transcript.

Anticancer research - 1 Jan 2000

Angelopoulou Katerina, Spiropoulou Tonia, Stathopoulou Aliki, Dimitroulopoulos Dimitris, Malamos Nikos, Georgoulias Vassilis, Paraskevas Emanouil, Lianidou Evi S

Abstract excerpt

BACKGROUND: Telomerase is a general diagnostic and prognostic molecular tumor marker since it is expressed in the majority of human tumors in contrast to most healthy tissues. Alternate splicing of human telomerase reverse transcriptase (hTERT) has been shown to affect telomerase activity. PATIENTS AND METHODS: We have developed a hybridization assay that selectively detects the hTERT beta-plus transcript....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to Biopsy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biotinylation

Share to Colonic Neoplasms

Share to In Situ Hybridization

Share to Luminescent Measurements

Share to Rectal Neoplasms

Share to Telomerase

Source

Identifiers

PMID: 14981931

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Development of a highly sensitive RT-PCR luminometric hybridization assay for human telomerase reverse-transcriptase beta-plus transcript.PMID 14981931Read ↗

Ratiometric Fluorescent Biosensor for Visual Discrimination of Cancer Cells with Different Telomerase Expression LevelsSemantic proximity Read ↗

Real-Time Reverse Transcription-PCR Assay for Future Management of ERBB2-based Clinical ApplicationsSemantic proximity Read ↗

A rapid, useful and quantitative method to measure telomerase activity by hybridization protection assay connected with a telomeric repeat amplification protocolSemantic proximity Read ↗

Quantification of hTERT Splice Variants in Melanoma by SYBR Green Real-time Polymerase Chain Reaction Indicates a Negative Regulatory Role for the β Deletion VariantSemantic proximity Read ↗

Real-Time RT-PCR Quantification of Human Telomerase Reverse Transcriptase Splice Variants in Tumor Cell Lines and Non–Small Cell Lung CancerSemantic proximity Read ↗

hTERT mRNA expression correlates with telomerase activity in human breast cancerSemantic proximity Read ↗

Quantitation of HER2 and telomerase biomarkers in solid tumors with IgY antibodies and nanocrystal detectionSemantic proximity Read ↗

Mammaglobin as a Novel Breast Cancer Biomarker: Multigene Reverse Transcription-PCR Assay and Sandwich ELISASemantic proximity Read ↗

Clinical implications of quantitative real-time RT–PCR analysis of hTERT gene expression in human gliomasSemantic proximity Read ↗

Quantitative assessment of human beta-globin gene expression in vitro by TaqMan real-time reverse transcription-PCR: comparison with competitive reverse transcription-PCR and application to mutations or deletions in noncoding regions.Semantic proximity Read ↗

Integrated Nanosensors to Determine Levels and Functional Activity of Human TelomeraseSemantic proximity Read ↗

Molecular assay to generate expression profile of eight estrogen receptor alpha isoform mRNA copy numbers in picogram amounts of total RNA from breast cancer tissues.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.