Growth Factor Deprivation Induces an Alternative Non-apoptotic Death Mechanism That Is Inhibited by Bcl2 in Cells Derived from Neural Precursor Cells

Abstract excerpt

Although apoptosis has been considered the typical mechanism for physiological cell death, presently alternative mechanisms need to be considered. We previously showed that fibroblast growth factor-2 (FGF2) could act as a survival factor for neural precursor cells. To study the death mechanism activated by the absence of this growth factor, we followed the changes in cell morphology and determined cell viability...

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