Article
Energetic depression caused by mitochondrial dysfunction.
Molecular and cellular biochemistry - 1 Jan 2004
Gellerich Frank Norbert, Trumbeckaite Sonata, Müller Tobias, Deschauer Marcus, Chen Ying, Gizatullina Zemfira, Zierz Stephan
Abstract excerpt
Mitochondria, providing most of ATP needed for cell work, realizing numerous specific functions as biosyntheses or degradations, contributing to Ca2+ signalling also play a key role in the pathways to cell death. Impairment of mitochondrial functions caused by mutations of mt-genome and by acute processes are responsible for numerous diseases. The relations between changes on the level of molecules and the...
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