Article
A gene-specific DNA sequencing chip for exploring molecular evolutionary change.
Nucleic acids research - 1 Jan 2004
Fedrigo Olivier, Naylor Gavin
Abstract excerpt
Sequencing by hybridization (SBH) approaches to DNA sequencing face two conflicting constraints. First, in order to ensure that the target DNA binds reliably, the oligonucleotide probes that are attached to the chip array must be >15 bp in length. Secondly, the total number of possible 15 bp olig...
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