Tracking disease genes by reverse genetics.

doi:10.1016/0022-3956(92)90035-m

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Article

Tracking disease genes by reverse genetics.

Journal of psychiatric research - 1 Oct 1992

Pignatti P F, Turco A E

Abstract excerpt

Increasingly, human genes are being identified by the "reverse genetics", or "positional cloning" approach. This molecular genetic strategy is particularly useful in mental illness, for which no readily detectable functional alterations are present to indicate candidate genes. The positional clon...

Topics

Chromosome Mapping
Cloning, Molecular
Fragile X Syndrome
Genetic Linkage
Genotype
Humans
Mental Disorders
Models, Genetic
Pedigree
Phenotype

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