Article
Association of apolipoprotein E polymorphisms with normal tension glaucoma in a Chinese population.
Journal of glaucoma - 1 Jun 2006
Lam Ching Yan, Fan Bao Jian, Wang Dan Yi, Tam Pancy Oi Sin, Yung Tham Clement Chee, Leung Dexter Yu Lung, Ping Fan Dorothy Shu, Chiu Lam Dennis Shun, Pang Chi Pui
Abstract excerpt
PURPOSE: To evaluate the role of apolipoprotein E (APOE) polymorphisms in primary open angle glaucoma (POAG). METHODS: A cohort of 400 unrelated Chinese POAG patients was examined, including 294 cases of high tension glaucoma (HTG) and 106 with normal tension glaucoma (NTG). Also studied were 300 unrelated Chinese control subjects. The genotypes of the APOE polymorphisms in exon 4 and in the promoter at positions...
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