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Article

Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut.

Proceedings of the National Academy of Sciences of the United States of America - 17 Feb 2004

Suzuki Keiichiro, Meek Bob, Doi Yasuko, Muramatsu Masamichi, Chiba Tsutomu, Honjo Tasuku, Fagarasan Sidonia

Abstract excerpt

The mechanism to maintain homeostasis of the gut microbiota remains largely unknown despite its critical role in the body defense. In the intestines of mice with deficiency of activation-induced cytidine deaminase (AID), the absence of hypermutated IgA is partially compensated for by the presence...

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Source

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Identifiers

PMID: 14766966
DOI: 10.1073/pnas.0307317101
PMCID: PMC357038

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14766966-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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