Article
Genotyping of Mycobacterium leprae on the basis of the polymorphism of TTC repeats for analysis of leprosy transmission.
Journal of clinical microbiology - 1 Feb 2004
Matsuoka Masanori, Zhang Liangfen, Budiawan Teky, Saeki Keisuke, Izumi Shinzo
Abstract excerpt
The polymorphism of TTC repeats in Mycobacterium leprae was examined using the bacilli obtained from residents in villages at North Maluku where M. leprae infections are highly endemic (as well as from patients at North Sulawesi of Indonesia) to elucidate the possible mode of leprosy transmission. TTC genotypes are stable for several generations of passages in nude mice footpads and, hence, are feasible for the...
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