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Article

Use of antisense RNA to modify the composition of cellulosomes produced by Clostridium cellulolyticum.

Molecular microbiology - 1 Jan 2004

Perret Stéphanie, Maamar Hédia, Bélaich Jean-Pierre, Tardif Chantal

Abstract excerpt

The enzymatic composition of the cellulosomes produced by Clostridium cellulolyticum was modified by inhibiting the synthesis of Cel48F that is the major cellulase of the cellulosomes. The strain ATCC 35319 (pSOSasrF) was developed to over-produce a 469 nucleotide-long antisense-RNA (asRNA) directed against the ribosome-binding site region and the beginning of the coding region of the cel48F mRNAs. The...

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PMID: 14756797
DOI: 10.1046/j.1365-2958.2003.03860.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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