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Article

Identification of patients with genetic risk factors of pancreatitis: impact on treatment and cancer prevention.

Digestive diseases (Basel, Switzerland) - 1 Jan 2003

Keim Volker

Abstract excerpt

Recent data suggest that genetic alterations are relevant risk factors for chronic pancreatitis. The highest risk is associated with autosomal-dominant mutations (N29I, R122H) of the cationic trypsinogen (PRSS1). Further mutations were identified in the genes of the pancreatic trypsin inhibitor (SPINK1) and in the cystic fibrosis transmembrane conductance regulator (CFTR). A remarkable finding was that both...

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Source

Identifiers

PMID: 14752225
DOI: 10.1159/000075358

Genes

CFTR
PRSS1
SPINK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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