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Article

Searching for cancer-associated gene polymorphisms: promises and obstacles.

Cancer letters - 10 Feb 2004

Imyanitov Evgeny N, Togo Alexandr V, Hanson Kaido P

Abstract excerpt

Low-penetrance genetic variations appear to form the most essential component of the heritability of cancer risk. Search for relevant polymorphic candidates faces significant obstacles, due to both the high number of potentially promising single nucleotide polymorphisms (SNPs) and the intrinsic difficulties in identification of weak gene-disease interactions. At present, extensive case-control studies can be...

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PMID: 14744529
DOI: 10.1016/j.canlet.2003.09.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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