Article
Association studies for finding cancer-susceptibility genetic variants.
Nature reviews. Cancer - 1 Nov 2004
Pharoah Paul D P, Dunning Alison M, Ponder Bruce A J, Easton Douglas F
Abstract excerpt
Cancer is the result of complex interactions between inherited and environmental factors. Known genes account for a small proportion of the heritability of cancer, and it is likely that many genes with modest effects are yet to be found. Genetic-association studies have been widely used in the search for such genes, but success has been limited so far. Increased knowledge of the function of genes and the...
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