Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy.

Immunity - 1 Jan 2004

Wang Helen Y, Lee Dean A, Peng Guangyong, Guo Zhong, Li Yanchun, Kiniwa Yukiko, Shevach Ethan M, Wang Rong Fu

Abstract excerpt

Regulatory T cells play an important role in the maintenance of immunological self-tolerance by suppressing immune responses against autoimmune diseases and cancer. Little is known, however, about the nature of the physiological target antigens for CD4(+) regulatory T (Treg) cells. Here we report...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Neoplasm
Share to Antigens, Surface
Share to CD4-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Division

Share to Forkhead Transcription Factors

Share to Immunotherapy

Share to Interferon-gamma

Share to Ligands

Source

Identifiers

PMID: 14738769
DOI: 10.1016/s1074-7613(03)00359-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14738769-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy.PMID 14738769Read ↗

Regulatory T Cells in Ovarian Cancer Are Characterized by a Highly Activated Phenotype Distinct from that in Melanoma.Semantic proximity Read ↗

Induced and natural regulatory T cells in human cancer.Semantic proximity Read ↗

TCF-1 regulates NKG2D expression on CD8 T cells during anti-tumor responsesSemantic proximity Read ↗

Tumor antigen‐specific CD4 + T cells in cancer immunity: from antigen identification to tumor prognosis and development of therapeutic strategiesSemantic proximity Read ↗

Coexpression of Inhibitory Receptors Enriches for Activated and Functional CD8+ T Cells in Murine Syngeneic Tumor ModelsSemantic proximity Read ↗

TCF-1 regulates NKG2D expression on CD8 T cells during anti-tumor responsesSemantic proximity Read ↗

Natural and Induced T Regulatory Cells in CancerSemantic proximity Read ↗

The EGR2 targets LAG-3 and 4-1BB describe and regulate dysfunctional antigen-specific CD8+ T cells in the tumor microenvironmentSemantic proximity Read ↗

FOXP3+ Treg as a therapeutic target for promoting anti-tumor immunity.Semantic proximity Read ↗

LAG-3: from molecular functions to clinical applicationsSemantic proximity Read ↗

Regulatory T cell targeting in cancer: Emerging strategies in immunotherapySemantic proximity Read ↗

Lymphocyte-activation gene 3 in cancer immunotherapy: function, prognostic biomarker and therapeutic potentialsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.