Article
Breast cancer: the protective effect of pregnancy.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jan 2004
Medina Daniel
Abstract excerpt
It has been firmly established in epidemiological studies that early full-term pregnancy affords lifetime protection against the development of breast cancer. This phenomenon can be mimicked in rat and mouse models of mammary cancer in which the hormones estrogen and progesterone are given for 21 days. Carcinogen-induced proliferation is blocked as a consequence of hormone pretreatment. Among several genes...
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