Article
Role of steroid hormones and growth factors in breast cancer.
Clinical chemistry and laboratory medicine - 1 Oct 2002
Lai Leslie C
Abstract excerpt
Breast cancer is the most common cancer in women worldwide and its incidence is increasing. Oestrogens and mitogenic growth factors may play an important role in the development of breast cancer, whereas inhibitory growth factors may prevent the development of breast cancer. Only about 5 to 10% of cases of breast cancer are due to inheritance of mutations in the BRCA1 or BRCA2 tumour suppressor genes. Mutations...
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