Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[DNA damage and aging].

Nederlands tijdschrift voor geneeskunde - 27 Dec 2003

Molenaar J C

Abstract excerpt

At present the mouse is the ideal experimental animal for studying molecular biological processes in human diseases. Premature aging occurred in mice with an induced mutation that resulted in a defective DNA repair mechanism. Compared to normal unmanipulated mice they exhibited characteristic symptoms of premature aging, such as premature greying, aging of the skin, osteoporosis, kyphosis, early menopause and a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Aging, Premature
Share to DNA Damage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Repair

Share to Mutation

Share to Oxidative Stress

Source

Identifiers

PMID: 14723025

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[DNA damage and aging].PMID 14723025Read ↗

DNA Damage, Aging, and CancerSemantic proximity Read ↗

DNA double-strand breaks: a potential causative factor for mammalian aging?Semantic proximity Read ↗

[Life without DNA repair].Semantic proximity Read ↗

DNA double strand break repair, aging and the chromatin connection.Semantic proximity Read ↗

[The molecular basis of cellular aging].Semantic proximity Read ↗

A review and appraisal of the DNA damage theory of ageing.Semantic proximity Read ↗

The role of DNA damage and repair in aging: new approaches to an old problem.Semantic proximity Read ↗

[Mitochondria, oxidative stress and aging].Semantic proximity Read ↗

Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaksSemantic proximity Read ↗

Genome instability and aging.Semantic proximity Read ↗

Mitochondrial dysfunction in mammalian ageing.Semantic proximity Read ↗

Modeling premature aging syndromes with the telomerase knockout mouse.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.