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Article

Bmi1, stem cells, and senescence regulation.

The Journal of clinical investigation - 1 Jan 2004

Park In-Kyung, Morrison Sean J, Clarke Michael F

Abstract excerpt

Stem cells generate the differentiated cell types within many organs throughout the lifespan of an organism and are thus ultimately responsible for the longevity of multicellular organisms. Therefore, senescence of stem cells must be prevented. Bmi1 is required for the maintenance of adult stem c...

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Identifiers

PMID: 14722607
DOI: 10.1172/JCI20800
PMCID: PMC311443

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14722607-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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