Article
Histidine 167 is the phosphate acceptor in glucose-6-phosphatase-beta forming a phosphohistidine enzyme intermediate during catalysis.
The Journal of biological chemistry - 26 Mar 2004
Ghosh Abhijit, Shieh Jeng-Jer, Pan Chi-Jiunn, Chou Janice Yang
Abstract excerpt
The glucose-6-phosphatase (Glc-6-Pase) family comprises two active endoplasmic reticulum (ER)-associated isozymes: the liver/kidney/intestine Glc-6-Pase-alpha and the ubiquitous Glc-6-Pase-beta. Both share similar kinetic properties. Sequence alignments predict the two proteins are structurally s...
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