Molecular abnormality of a unique Japanese glucose-6-phosphate dehydrogenase variant (G6PD Kobe) with a greatly increased affinity for galactose-6-phosphate.

doi:10.1002/ajh.2830450217

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Article

Molecular abnormality of a unique Japanese glucose-6-phosphate dehydrogenase variant (G6PD Kobe) with a greatly increased affinity for galactose-6-phosphate.

American journal of hematology - 1 Feb 1994

Hirono A, Nakayama S, Fujii H, Miwa S

Abstract excerpt

Systematic molecular analysis of a Japanese class 1 glucose-6-phosphate dehydrogenase (G6PD) variant (G6PD Kobe) cDNA revealed a unique nucleotide substitution (1318 C to T) in exon 11, which predicts a substitution of leucine for phenylalanine at residue 440. This substitution is located in a re...

Topics

Base Sequence
Galactosephosphates
Genetic Variation
Glucosephosphate Dehydrogenase
Humans
Molecular Sequence Data

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