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REVIEW ARTICLE: Immunology of Pre‐Eclampsia

23 Mar 2010

Abstract excerpt

Pre-eclampsia develops in stages, only the last being the clinical illness. This is generated by a non-specific, systemic (vascular), inflammatory response, secondary to placental oxidative stress and not by reactivity to fetal alloantigens. However, maternal adaptation to fetal (paternal alloantigens) is crucial in the earlier stages. A pre-conceptual phase involves maternal tolerization to paternal antigens by...

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PMID: 20331588
DOI: 10.1111/j.1600-0897.2010.00831.x

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