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The regulation of ISG20 expression on SARS-CoV-2 infection in cancer patients and healthy individuals

13 Sept 2022

Abstract excerpt

ISG20 inhibits viruses such as SARS-CoV-2 invasion; however, details of its expression and regulation with viral susceptibility remain to be elucidated. The present study analyzed ISG20 expression, isoform information, survival rate, methylation patterns, immune cell infiltration, and COVID-19 outcomes in healthy and cancerous individuals. Cordycepin (CD) and N6, N6-dimethyladenosine (m62A) were used to treat...

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PMID: 36177004
DOI: 10.3389/fimmu.2022.958898

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