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Article

Axonal defects in mouse models of motoneuron disease.

Journal of neurobiology - 5 Feb 2004

Jablonka Sibylle, Wiese Stefan, Sendtner Michael

Abstract excerpt

Human motoneuron disease is characterized by loss of motor endplates, axonal degeneration, and cell death of motoneurons. The identification of the underlying gene defects for familial ALS, spinal muscular atrophy (SMA), and spinal muscular atrophy with respiratory distress (SMARD) has pointed to distinct pathophysiological mechanisms that are responsible for the various forms of the disease. Accumulating...

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PMID: 14704958
DOI: 10.1002/neu.10313

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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