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Article

Domainal organization of the lower eukaryotic homologs of the yeast RNA polymerase II core subunit Rpb7 reflects functional conservation.

Nucleic acids research - 1 Jan 2004

Singh Sunanda R, Rekha Nambudiry, Pillai Beena, Singh Vijender, Naorem Aruna, Sampath Vinaya, Srinivasan N, Sadhale Parag P

Abstract excerpt

The subcomplex of Rpb4 and Rpb7 subunits of RNA pol II in Saccharomyces cerevisiae is known to be an important determinant of transcription under a variety of physiological stresses. In S.cerevisiae, RPB7 is essential for cell viability while rpb4 null strains are temperature sensitive at low and high temperatures. The rpb4 null strain also shows defect in sporulation and a predisposed state of pseudohyphal...

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Identifiers

PMID: 14704357
DOI: 10.1093/nar/gkh163
PMCID: PMC373273

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