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Article

Microevolution and virulence of dengue viruses.

Advances in virus research - 1 Jan 2003

Rico-Hesse Rebeca

Abstract excerpt

The evolution of dengue viruses has had a major impact on their virulence for humans and on the epidemiology of dengue disease around the world. Although antigenic and genetic differences in virus strains had become evident, it is mainly due to the lack of animal models of disease that has made it difficult to detect differences in virulence of dengue viruses. However, phylogenetic studies of many different...

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Identifiers

PMID: 14696333
DOI: 10.1016/s0065-3527(03)59009-1
PMCID: PMC3045824

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