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Molecular and in vitro analysis of eight dengue type 2 viruses isolated from patients exhibiting different disease severities.

Virology - 10 May 1998

Mangada M N, Igarashi A

Abstract excerpt

Potential genetic determinants of dengue virulence were studied by sequencing the entire genomes of eight dengue 2 virus strains isolated from patients exhibiting different disease severities during an epidemic season in northeastern Thailand in 1993. The isolates came from one dengue shock syndrome (ThNH-7/93), three dengue hemorrhagic fever, and four dengue fever patients. Phylogenetic analysis showed that the...

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PMID: 9601513
DOI: 10.1006/viro.1998.9093

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