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The β<sub>II</sub> isotype of tubulin is present in the cell nuclei of a variety of cancers

16 Dec 2003

Abstract excerpt

Tubulin, the subunit protein of microtubules, has generally been thought to be exclusively a cytoplasmic protein in higher eukaryotes. We have previously shown that cultured rat kidney mesangial cells contain the betaII isotype of tubulin in their nuclei in the form of an alphabetaII dimer [Walss et al., 1999: Cell Motil. Cytoskeleton 42:274-284, 1999]. More recently, we examined a variety of cancerous and...

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PMID: 14691949
DOI: 10.1002/cm.10157

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