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Article

Variants of the myocilin gene in Japanese patients with normal-tension glaucoma.

Ophthalmic research - 1 Jan 2000

Izumi Kanako, Mashima Yukihiko, Obazawa Minoru, Ohtake Yuichiro, Tanino Tomihiko, Miyata Hiroshi, Zhang Qiang, Oguchi Yoshihisa, Tanaka Yasuhiko, Iwata Takeshi

Abstract excerpt

Myocilin (MYOC) mutations are associated with juvenile- and adult-onset primary open-angle glaucoma (POAG). The purpose of this study was to determine whether MYOC gene mutations are associated with normal-tension glaucoma (NTG). The prevalence of MYOC mutations was determined in 80 Japanese NTG patients and 100 control subjects. In addition, the expression of mutant MYOC was determined by transforming COS-1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14688426
DOI: 10.1159/000074075

Genes

MYOC

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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