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Relationship between ROS production, apoptosis and DNA denaturation in spermatozoa from patients examined for infertility

31 Dec 2003

Abstract excerpt

BACKGROUND: The aim of this study was to examine the role of apoptosis and reactive oxygen species (ROS) in inducing DNA damage in ejaculated spermatozoa. METHODS: We examined ejaculated spermatozoa from 31 patients examined for infertility and 19 healthy donors for apoptosis, production of ROS and DNA damage using annexin V binding, chemiluminescence assay and sperm chromatin structure assay. RESULTS: The...

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PMID: 14688171
DOI: 10.1093/humrep/deh024

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