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Article

Direct measurement of in vivo flux differences between electrophoretic variants of G6PD from Drosophila melanogaster.

Genetics - 1 Nov 1992

Labate J, Eanes W F

Abstract excerpt

Demonstrating that naturally occurring enzyme polymorphisms significantly impact metabolic pathway flux is a fundamental step in examining the possible adaptive significance of such polymorphisms. In earlier studies of the glucose-6-phosphate dehydrogenase (G6PD) polymorphism in Drosophila melanogaster, we used two different methods, exploiting both genotype-dependent interactions with the 6Pgd locus, and...

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Identifiers

PMID: 1468630
DOI: 10.1093/genetics/132.3.783
PMCID: PMC1205214

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