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Article

Extensive amino acid polymorphism at the pgm locus is consistent with adaptive protein evolution in Drosophila melanogaster.

Genetics - 1 Dec 2000

Verrelli B C, Eanes W F

Abstract excerpt

PGM plays a central role in the glycolytic pathway at the branch point leading to glycogen metabolism and is highly polymorphic in allozyme studies of many species. We have characterized the nucleotide diversity across the Pgm gene in Drosophila melanogaster and D. simulans to investigate the role that protein polymorphism plays at this crucial metabolic branch point shared with several other enzymes. Although D....

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Identifiers

PMID: 11102370
DOI: 10.1093/genetics/156.4.1737
PMCID: PMC1461360

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