Article
Aberrant responses in social interaction of dopamine transporter knockout mice.
Behavioural brain research - 5 Jan 2004
Rodriguiz Ramona M, Chu Richard, Caron Marc G, Wetsel William C
Abstract excerpt
The dopamine (DA) transporter (DAT) controls the temporal and spatial resolution of dopaminergic neurotransmission. Disruption of the Dat1 gene in mice leads to increased extracellular DA concentrations and reduced expression of D1- and D2-like receptors in striatum. The mutants are hyperactive i...
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