Article
REC, a new member of the MCM-related protein family, is required for meiotic recombination in Drosophila.
Genes & genetic systems - 1 Oct 2003
Matsubayashi Hiroshi, Yamamoto Masa-Toshi
Abstract excerpt
rec mutations result in an extremely low level of recombination and a high frequency of primary non-disjunction in the female meiosis of Drosophila melanogaster. Here we demonstrate that the rec gene encodes a novel protein related to the mini-chromosome maintenance (MCM) proteins. Six MCM proteins (MCM2-7) are conserved in eukaryotic genomes, and they function as heterohexamers in the initiation and progression...
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