Article
Association between IL-1ra gene polymorphism and premature delivery.
Biology of the neonate - 1 Jan 2004
Bessler H, Osovsky M, Sirota L
Abstract excerpt
IL-1 receptor antagonist (IL-1ra) gene polymorphism was examined in 95 Israeli preterm newborns and compared to that of adult volunteers. The genotype was determined using PCR amplification of the variable region of intron 2 of the IL-1ra gene. The IL-1raA1 allele was found to be predominant in the two groups. However, a significant higher frequency of IL-1raA2 allele was found in preterm newborns. The difference...
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