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Article

Molecular basis for the treatment of achondroplasia.

Hormone research - 1 Jan 2003

Yamanaka Yoshitaka, Ueda Koso, Seino Yoshiki, Tanaka Hiroyuki

Abstract excerpt

Achondroplasia (ACH), the most common form of short-limbed dwarfism, and its related disorders are caused by constitutively activated point-mutated fibroblast growth factor receptor 3 (FGFR3). Recent studies have provided a large body of evidence to prove chondrocyte proliferation and differentiation in these disorders. However, little is known about the possible effects of the FGFR3 mutants on apoptosis of...

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Source

Identifiers

PMID: 14671399
DOI: 10.1159/000074503

Genes

FGFR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Molecular basis for the treatment of achondroplasia.PMID 14671399Read ↗

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Novel therapeutic approaches for the treatment of achondroplasia.Semantic proximity Read ↗

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