Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Fibroblast growth factor receptor and achondroplasia].

Clinical calcium - 1 Nov 2006

Tanaka Hiroyuki

Abstract excerpt

Fibroblast growth factor receptor 3 (FGFR3) has been establishing its position in growth plate cartilage after the identification as a responsible gene for achondroplasia. The major pathway of the pathogenesis in achondroplasia is the suppression of parathyroid hormone-related protein (PTHrP)-parathyroid hormone receptor (PTHR) system, which is mainly mediated by extracellular signal regulated kinase (ERK)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Achondroplasia
Share to Extracellular Signal-Regulated MAP Kinases
Share to FGFR3 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Parathyroid Hormone-Related Protein

Share to Receptors, Fibroblast Growth Factor

Share to Signal Transduction

Share to STAT1 Transcription Factor

Source

Identifiers

PMID: 17079857
DOI: CliCa061118881893

Genes

FGFR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Fibroblast growth factor receptor and achondroplasia].PMID 17079857Read ↗

[Cytokines in bone diseases. FGF receptor signaling and achondroplasia/hypochondroplasia].Semantic proximity Read ↗

[From gene to disease; achondroplasia and other skeletal dysplasias due to an activating mutation in the fibroblast growth factor].Semantic proximity Read ↗

Achondroplasia: pathogenesis and implications for future treatment.Semantic proximity Read ↗

FGFR3 targeting strategies for achondroplasia.Semantic proximity Read ↗

Novel therapeutic approaches for the treatment of achondroplasia.Semantic proximity Read ↗

Achondroplasia: from genotype to phenotype.Semantic proximity Read ↗

International Consensus Statement on the diagnosis, multidisciplinary management and lifelong care of individuals with achondroplasia.Semantic proximity Read ↗

Knock-in human FGFR3 achondroplasia mutation as a mouse model for human skeletal dysplasiaSemantic proximity Read ↗

Sixteen years and counting: the current understanding of fibroblast growth factor receptor 3 (FGFR3) signaling in skeletal dysplasias.Semantic proximity Read ↗

[Hereditary skeletal dysplasias and FGFR3 and PTHR1 signaling pathways].Semantic proximity Read ↗

FGFR3 gene mutations in transmembrane domain in Chinese achondroplasia and hypochondroplasia patients.Semantic proximity Read ↗

FGFR3 mutation causes abnormal membranous ossification in achondroplasiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.