Article
Atypical epithelial proliferation in fallopian tubes in prophylactic salpingo-oophorectomy specimens from BRCA1 and BRCA2 germline mutation carriers.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Jan 2004
Carcangiu Maria L, Radice Paolo, Manoukian Siranoush, Spatti Gianbattista, Gobbo Morena, Pensotti Valeria, Crucianelli Rosella, Pasini Barbara
Abstract excerpt
Although growing numbers of tubal carcinomas in carriers of BRCA1 and BRCA2 germline mutations have been reported, very little is known about the nature and frequency of their possible precursor lesions. The aim of this study is to investigate the occurrence of atypical proliferative tubal lesions in grossly normal fallopian tubes from 26 women with BRCA1 and BRCA2 germline mutations who underwent prophylactic...
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