Article
Molecular analysis of endometrial hyperplasia in HNPCC-suspicious patients may predict progression to endometrial carcinoma.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Jan 2004
Sutter Christian, Dallenbach-Hellweg Gisela, Schmidt Dietmar, Baehring Joachim, Bielau Simone, von Knebel Doeberitz Magnus, Gebert Johannes
Abstract excerpt
Women predisposed to hereditary nonpolyposis colorectal cancer are at high risk of developing endometrial carcinoma at a young age. Hereditary nonpolyposis colorectal cancer-associated endometrial carcinomas are of the endometrioid type, usually arise from complex atypical hyperplasia, and often show microsatellite instability. To identify occult hereditary nonpolyposis colorectal cancer individuals among...
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