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Article

X-linked inhibitor of apoptosis (XIAP) confers human trophoblast cell resistance to Fas-mediated apoptosis

9 Dec 2003

Abstract excerpt

Apoptosis occurs in the placenta throughout gestation, with a greater frequency near term in comparison to the first trimester. The Fas/FasL system represents one of the main apoptotic pathways controlling placental apoptosis. Although first trimester trophoblast cells express both Fas and FasL, they are resistant to Fas-induced apoptosis. Therefore, trophoblast resistance to Fas-mediated apoptosis may be due to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 14665704
DOI: 10.1093/molehr/gah001

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