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Article

The Role of Placental Fas Ligand in Maintaining Immune Privilege at Maternal - Fetal Interfaces

1 Mar 1999

Abstract excerpt

It is now recognized that immunosuppressive factors synthesized by placenta may play a critical role in the maintenance of pregnancy. Over the last several years our group and others have formulated a hypothesis that trophoblast Fas ligand (FasL) plays an important role in maintaining fetal immune privilege in human pregnancy by actively promoting apoptosis (programmed cell death) of activated maternal...

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PMID: 10406074
DOI: 10.1055/s-2007-1016210

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The Role of Placental Fas Ligand in Maintaining Immune Privilege at Maternal - Fetal InterfacesPMID 10406074Read ↗

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Decidual Macrophages Are Significantly Increased in Spontaneous Miscarriages and Over-Express FasL: A Potential Role for Macrophages in Trophoblast ApoptosisSemantic proximity Read ↗

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