Article
Association between small apolipoprotein(a) isoforms and frontotemporal dementia in humans.
Neuroscience letters - 26 Dec 2003
Emanuele Enzo, Peros Emmanouil, Tomaino Carmine, Feudatari Enrica, Bernardi Livia, Binetti Giuliano, Maletta Raffaele, Micieli Giuseppe, Bruni Amalia Cecilia, Geroldi Diego
Abstract excerpt
Apolipoprotein(a) [apo(a)] is a genetically polymorphic glycoprotein that has several similarities to apolipoprotein E. However, its role as a risk factor for frontotemporal dementia (FTD) remains to be elucidated. We therefore investigated the effect of an apo(a) polymorphism on the incidence of FTD in a sample of Caucasian Italian patients. From the entire group of FTD patients (n=54), 55.6% of the subjects had...
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