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Article

Hypercholesterolemia associated with splice-junction variation of inter-alpha-trypsin inhibitor heavy chain 4 (ITIH4) gene.

Journal of human genetics - 1 Jan 2004

Fujita Yuko, Ezura Yoichi, Emi Mitsuru, Sato Keiko, Takada Daisuke, Iino Yasuhiko, Katayama Yasuo, Takahashi Kaneo, Kamimura Kouhei, Bujo Hideaki, Saito Yasushi

Abstract excerpt

Factors predisposing to the phenotypic features of higher total cholesterol (T-Cho) have not been clearly defined. Here we report an association between a C/T single nucleotide polymorphism at IVS17+8 in the inter-alpha-trypsin inhibitor heavy chain 4 gene (ITIH4) and plasma total cholesterol levels in 351 adult individuals from an east-central area of Japan. Age and gender-adjusted levels of plasma T-Cho,...

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Source

Identifiers

PMID: 14661079
DOI: 10.1007/s10038-003-0101-8

Genes

ITIH4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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