Article
HMG-D and histone H1 alter the local accessibility of nucleosomal DNA.
Nucleic acids research - 15 Dec 2003
Ragab Anan, Travers Andrew
Abstract excerpt
There is evidence that HMGB proteins facilitate, while linker histones inhibit chromatin remodelling, respectively. We have examined the effects of HMG-D and histone H1/H5 on accessibility of nucleosomal DNA. Using the 601.2 nucleosome positioning sequence designed by Widom and colleagues we assembled nucleosomes in vitro and probed DNA accessibility with restriction enzymes in the presence or absence of HMG-D...
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