Article
Stella is a maternal effect gene required for normal early development in mice.
Current biology : CB - 2 Dec 2003
Payer Bernhard, Saitou Mitinori, Barton Sheila C, Thresher Rosemary, Dixon John P C, Zahn Dirk, Colledge William H, Carlton Mark B L, Nakano Toru, Surani M Azim
Abstract excerpt
stella is a novel gene specifically expressed in primordial germ cells, oocytes, preimplantation embryos, and pluripotent cells. It encodes a protein with a SAP-like domain and a splicing factor motif-like structure, suggesting possible roles in chromosomal organization or RNA processing. Here, we have investigated the effects of a targeted mutation of stella in mice. We show that while matings between...
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