Article
Chemokine gene polymorphisms associate with gender in patients with uveitis.
Tissue antigens - 1 Jan 2004
Chen Y, Vaughan R W, Kondeatis E, Fortune F, Graham E M, Stanford M R, Wallace G R
Abstract excerpt
Uveitis is an inflammatory condition of ocular tissue characterized by leukocyte infiltration, tissue damage, and decreased visual acuity. Chemokines have been implicated in the pathogenesis of uveitis. Polymorphisms in the genes encoding chemokines have been described as affecting chemokine production or function. We analyzed the frequency of single-nucleotide polymorphisms (SNPs) in genes encoding CCL2 (-2518...
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