Article
Altered expression of the septin gene, SEPT9, in ovarian neoplasia.
The Journal of pathology - 1 Dec 2003
Burrows James F, Chanduloy Severine, McIlhatton Michael A, Nagar Hans, Yeates Karen, Donaghy Paul, Price John, Godwin Andrew K, Johnston Patrick G, Russell S E Hilary
Abstract excerpt
The septin family of genes has been implicated in a variety of cellular processes including cytokinesis, membrane transport and fusion, exocytosis, and apoptosis. One member of the septin family maps to chromosome 17q25.3, a region commonly deleted in sporadic ovarian and breast tumours, and has also been identified as a fusion partner of MLL in acute myeloid leukaemias. The present study demonstrates that the...
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